Which Patients With Psychotic Depression Will Wind Up With Bipolar Disorder? Mental HealthBy Promises Behavioral HealthJuly 28, 2014Sometimes one illness transitions into another. Such is the case for some people with psychotic depression who start out with a form of unipolar depression and ultimately struggle with bipolar disorder. This is called conversion. A study looked for ways that clinicians can predict which patients with psychotic depression would convert to bipolar disorder.